Micronics Acquires License to Biosearch Technologies' Nucleic Acid Assay Chemistries

Company is advancing point-of-care molecular diagnostic infectious disease applications

REDMOND, WA – October 28, 2009 – Micronics, Inc., a leading developer of point-of-care molecular diagnostic products, announced today that it has entered into a license agreement with Biosearch Technologies, Inc. (Biosearch) for the right to make, have made, use and sell Micronics’ products that incorporate Biosearch’s proprietary fluorophores and quencher dyes for nucleic acid assays. Under the terms of the worldwide license, Biosearch has granted Micronics a royalty-free use of certain of its chemistries for inclusion in Micronics’ infectious disease tests for sale in underdeveloped countries.

Micronics is advancing a family of near patient, point-of-care molecular tests for infectious disease diagnosis and forensic testing. These tests employ Micronics’ microfluidics technologies, which enable substantial reductions in both the volume of a sample taken from a patient and the reagents required to perform a nucleic acid amplification assay. Micronics is advancing a portfolio of tests that are responsive to unmet needs in the infections disease sector worldwide, such as Shiga toxin producing E.coli, malaria and respiratory disease panels.

Biosearch’s proprietary line of fluorophores and quenchers, including the Black Hole Quencher (BHQ), CAL Fluor, and Quasar dye technologies, will be used by Micronics in conjunction with the molecular beacons probe technology that Micronics licensed from PHRI Properties. The BHQ dyes are the quenchers of choice for fluorescence-quenched probe applications in many nucleic acid assay testing methods. Most recently, the Centers for Disease Control and Prevention selected a BHQ dye as the core detection technology for use in the Influenza H1N1 (Swine Flu) real-time PCR test for distribution among public health and other qualified labs worldwide.

By incorporating molecular beacons with Biosearch fluorophores and BHQ dyes, Micronics’ test cartridges can perform either single or multiplex pathogen detection. Each test cartridge will contain all of the required test reagents for ease of use and non-refrigerated storage. The cartridge is processed by a lightweight, low-cost, battery or mains-powered instrument with software connectivity. Micronics’ tests are designed to provide a result in under thirty minutes, directly from sample acquisition in the sealed disposable test cartridge. 

About Micronics

Micronics is a privately-held company located in Redmond, Washington that is advancing a unique portfolio of point-of-care molecular diagnostic products for infectious disease diagnosis. The Company has developed a significant patent estate in microfluidics and related technologies that enable the processing of biological and environmental samples directly in disposable devices, and the performance of highly accurate and affordable tests in a fraction of the time required by most molecular diagnostic tests in use today. The Company also provides custom product development on behalf of partners and clients worldwide. For additional information, please visit www.micronics.net.

About Biosearch Technologies, Inc.

Biosearch Technologies, Inc. is a privately held, ISO 9001:2008 certified company, located in northern California. Founded in 1993, Biosearch is a leader in the design, development and manufacture of sophisticated oligonucleotide-based tools. Products include fluorophores (CAL Fluor®, Quasar® and Pulsar® dyes) and dark quenchers (Black Hole Quencher® dyes) to be included in custom-synthesized probe formats for real-time, quantitative PCR and other genomic-based applications.

In addition to basic R&D applications, Biosearch now leverages its demonstrated expertise in fully assembled kits and the cGMP manufacture of oligonucleotides for molecular diagnostic assays. As a Class I ASR manufacturer, Biosearch’s manufacturing processes conform to all applicable GMP requirements per 21 CFR Part 820. Biosearch markets include pharmaceutical, diagnostic IVD, biotech, ag/bio, environmental and food testing, public health, and biodefense sectors.

For additional information about Biosearch Technologies, Inc., contact info@biosearchtech.com or visit www.biosearchtech.com.

Micronics Contact
Karen Hedine
President /CEO
PH: 425-895-9197 x 126
Email: khedine@micronics.net


Biosearch Technologies Contact
Marc Beal, M.B.A.
Director of Corporate Development,
PH: (415) 883-8400
Email: marcb@biosearchtech.com
“Black Hole Quencher”, “BHQ”, “CAL Fluor”, and “Quasar” are registered trademarks of Biosearch Technologies, Inc.

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